Serine/threonine/tyrosine-interacting-like protein 1 (Dual specificity phosphatase inhibitor MK-STYX) (Dual specificity protein phosphatase 24) (Inactive dual specificity protein phosphatase MK-STYX) (Map kinase phosphatase-like protein MK-STYX)
1_MPGLL 6_ LCEPT 11_ ELYNI 16_ LNQAT 21_ KLSRL 26_ TDPNY 31_ LCLLD 36_ VRSKW 41_ EYDES 46_ HVITA 51_ LRVKK 56_ KNNEY 61_ LLPES 66_ VDLEC 71_ VKYCV 76_ VYDNN 81_ SSTLE 86_ ILLKD 91_ DDDDS 96_ DSDGD 101_ GKDLV 106_ PQAAI 111_ EYGRI 116_ LTRLT 121_ HHPVY 126_ ILKGG 131_ YERFS 136_ GTYHF 141_ LRTQK 146_ IIWMP 151_ QELDA 156_ FQPYP 161_ IEIVP 166_ GKVFV 171_ GNFSQ 176_ ACDPK 181_ IQKDL 186_ KIKAH 191_ VNVSM 196_ DTGPF 201_ FAGDA 206_ DKLLH 211_ IRIED 216_ SPEAQ 221_ ILPFL 226_ RHMCH 231_ FIEIH 236_ HHLGS 241_ VILIF 246_ STQGI 251_ SRSCA 256_ AIIAY 261_ LMHSN 266_ EQTLQ 271_ RSWAY 276_ VKKCK 281_ NNMCP 286_ NRGLV 291_ SQLLE 296_ WEKTI 301_ LGDSI 306_TNIMD
1: Catalytically inactive phosphatase (PubMed:20180778, PubMed:23163895). By binding to G3BP1, inhibits the formation of G3BP1-induced stress granules (PubMed:20180778, PubMed:23163895). Does not act by protecting the dephosphorylation of G3BP1 at 'Ser-149' (PubMed:23163895). Inhibits PTPMT1 phosphatase activity (PubMed:24709986). By inhibiting PTPMT1, positively regulates intrinsic apoptosis (PubMed:21262771). May play a role in the formation of neurites during neuronal development (PubMed:29250526)