Choline/ethanolaminephosphotransferase 1 (hCEPT1) (EC 2.7.8.1) (EC 2.7.8.2) (1-alkenyl-2-acylglycerol choline phosphotransferase) (EC 2.7.8.22)
1_MSGHR 6_ STRKR 11_ CGDSH 16_ PESPV 21_ GFGHM 26_ STTGC 31_ VLNKL 36_ FQLPT 41_ PPLSR 46_ HQLKR 51_ LEEHR 56_ YQSAG 61_ RSLLE 66_ PLMQG 71_ YWEWL 76_ VRRVP 81_ SWIAP 86_ NLITI 91_ IGLSI 96_ NICTT 101_ ILLVF 106_ YCPTA 111_ TEQAP 116_ LWAYI 121_ ACACG 126_ LFIYQ 131_ SLDAI 136_ DGKQA 141_ RRTNS 146_ SSPLG 151_ ELFDH 156_ GCDSL 161_ STVFV 166_ VLGTC 171_ IAVQL 176_ GTNPD 181_ WMFFC 186_ CFAGT 191_ FMFYC 196_ AHWQT 201_ YVSGT 206_ LRFGI 211_ IDVTE 216_ VQIFI 221_ IIMHL 226_ LAVIG 231_ GPPFW 236_ QSMIP 241_ VLNIQ 246_ MKIFP 251_ ALCTV 256_ AGTIF 261_ SCTNY 266_ FRVIF 271_ TGGVG 276_ KNGST 281_ IAGTS 286_ VLSPF 291_ LHIGS 296_ VITLA 301_ AMIYK 306_ KSAVQ 311_ LFEKH 316_ PCLYI 321_ LTFGF 326_ VSAKI 331_ TNKLV 336_ VAHMT 341_ KSEMH 346_ LHDTA 351_ FIGPA 356_ LLFLD 361_ QYFNS 366_ FIDEY 371_ IVLWI 376_ ALVFS 381_ FFDLI 386_ RYCVS 391_ VCNQI 396_ ASHLH 401_ IHVFR 406_ IKVST 411_AHSNH
1: Catalyzes both phosphatidylcholine and phosphatidylethanolamine biosynthesis from CDP-choline and CDP-ethanolamine, respectively (PubMed:10191259, PubMed:10893425, PubMed:12216837, PubMed:37137909). Involved in protein-dependent process of phospholipid transport to distribute phosphatidyl choline to the lumenal surface (PubMed:10191259, PubMed:10893425, PubMed:12216837). Has a higher cholinephosphotransferase activity than ethanolaminephosphotransferase activity (PubMed:10191259, PubMed:12216837)