Wiskott-Aldrich syndrome protein family member 2 (WASP family protein member 2) (Protein WAVE-2) (Verprolin homology domain-containing protein 2)
1_MPLVT 6_ RNIEP 11_ RHLCR 16_ QTLPS 21_ VRSEL 26_ ECVTN 31_ ITLAN 36_ VIRQL 41_ GSLSK 46_ YAEDI 51_ FGELF 56_ TQANT 61_ FASRV 66_ SSLAE 71_ RVDRL 76_ QVKVT 81_ QLDPK 86_ EEEVS 91_ LQGIN 96_ TRKAF 101_ RSSTI 106_ QDQKL 111_ FDRNS 116_ LPVPV 121_ LETYN 126_ TCDTP 131_ PPLNN 136_ LTPYR 141_ DDGKE 146_ ALKFY 151_ TDPSY 156_ FFDLW 161_ KEKML 166_ QDTKD 171_ IMKEK 176_ RKHRK 181_ EKKDN 186_ PNRGN 191_ VNPRK 196_ IKTRK 201_ EEWEK 206_ MKMGQ 211_ EFVES 216_ KEKLG 221_ TSGYP 226_ PTLVY 231_ QNGSI 236_ GCVEN 241_ VDASS 246_ YPPPP 251_ QSDSA 256_ SSPSP 261_ SFSED 266_ NLPPP 271_ PAEFS 276_ YPVDN 281_ QRGSG 286_ LAGPK 291_ RSSVV 296_ SPSHP 301_ PPAPP 306_ LGSPP 311_ GPKPG 316_ FAPPP 321_ APPPP 326_ PPPMI 331_ GIPPP 336_ PPPVG 341_ FGSPG 346_ TPPPP 351_ SPPSF 356_ PPHPD 361_ FAAPP 366_ PPPPP 371_ PAADY 376_ PTLPP 381_ PPLSQ 386_ PTGGA 391_ PPPPP 396_ PPPPP 401_ GPPPP 406_ PFTGA 411_ DGQPA 416_ IPPPL 421_ SDTTK 426_ PKSSL 431_ PAVSD 436_ ARSDL 441_ LSAIR 446_ QGFQL 451_ RRVEE 456_ QREQE 461_ KRDVV 466_ GNDVA 471_ TILSR 476_ RIAVE 481_ YSDSE 486_ DDSSE 491_FDEDD
1: Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex