Gene name: LY96

Uniprot entry:

Q9Y6Y9

Protein names:

Lymphocyte antigen 96 (Ly-96) (ESOP-1) (Protein MD-2)

Protein sequence:

1_MLPFL 6_ FFSTL 11_ FSSIF 16_ TEAQK 21_ QYWVC 26_ NSSDA 31_ SISYT 36_ YCDKM 41_ QYPIS 46_ INVNP 51_ CIELK 56_ RSKGL 61_ LHIFY 66_ IPRRD 71_ LKQLY 76_ FNLYI 81_ TVNTM 86_ NLPKR 91_ KEVIC 96_ RGSDD 101_ DYSFC 106_ RALKG 111_ ETVNT 116_ TISFS 121_ FKGIK 126_ FSKGK 131_ YKCVV 136_ EAISG 141_ SPEEM 146_ LFCLE 151_FVILH

Protein annotations

Protein functions:

1: Binds bacterial lipopolysaccharide (LPS) (PubMed:17569869, PubMed:17803912). Cooperates with TLR4 in the innate immune response to bacterial lipopolysaccharide (LPS), and with TLR2 in the response to cell wall components from Gram-positive and Gram-negative bacteria (PubMed:11160242, PubMed:11593030). Enhances TLR4-dependent activation of NF-kappa-B (PubMed:10359581). Cells expressing both LY96 and TLR4, but not TLR4 alone, respond to LPS (PubMed:10359581)