Alpha-1,3-galactosyltransferase 2 (EC 2.4.1.87) (Isoglobotriaosylceramide synthase) (iGb3 synthase) (iGb3S)
1_MALKE 6_ GLRAW 11_ KRIFW 16_ RQILL 21_ TLGLL 26_ GLFLY 31_ GLPKF 36_ RHLEA 41_ LIPMG 46_ VCPSA 51_ TMSQL 56_ RDNFT 61_ GALRP 66_ WARPE 71_ VLTCT 76_ PWGAP 81_ IIWDG 86_ SFDPD 91_ VAKQE 96_ ARQQN 101_ LTIGL 106_ TIFAV 111_ GRYLE 116_ KYLER 121_ FLETA 126_ EQHFM 131_ AGQSV 136_ MYYVF 141_ TELPG 146_ AVPRV 151_ ALGPG 156_ RRLPV 161_ ERVAR 166_ ERRWQ 171_ DVSMA 176_ RMRTL 181_ HAALG 186_ GLPGR 191_ EAHFM 196_ FCMDV 201_ DQHFS 206_ GTFGP 211_ EALAE 216_ SVAQL 221_ HSWHY 226_ HWPSW 231_ LLPFE 236_ RDAHS 241_ AAAMA 246_ WGQGD 251_ FYNHA 256_ AVFGG 261_ SVAAL 266_ RGLTA 271_ HCAGG 276_ LDWDR 281_ ARGLE 286_ ARWHD 291_ ESHLN 296_ KFFWL 301_ HKPAK 306_ VLSPE 311_ FCWSP 316_ DIGPR 321_ AEIRR 326_ PRLLW 331_APKGY
1: Synthesizes the galactose-alpha(1,3)-galactose group on the glycosphingolipid isoglobotrihexosylceramide or isogloboside 3 (iGb3) by catalyzing the transfer of galactose from UDP-Galactose to its acceptor molecule Gal-beta-1,4-Glc-ceramide. Can also catalyze the addition of galactose to iGb3 itself to form polygalactose structures